

Karthus vs Kai’Sa Counter Pick
Matchup Summary
What the Data Means
This page breaks down the Karthus vs Kai’Sa matchup in League of Legends in the ADC role, using current ranked statistics. Across 594 recorded games on patch 16.13.1, Karthus wins 57.6% of the time against Kai’Sa. That puts the matchup in Karthus’s favor — the win rate sits above break-even, making Kai’Sa one of the targets Karthus punishes most reliably.
Win rate and sample size are the two numbers to trust here: the more games behind a matchup, the more stable its rating from patch to patch. The stats refresh automatically every 48 hours from ranked games at Emerald and above, so this page always reflects the current meta rather than an old snapshot. For itemization and runes, open the current Karthus build; both champions’ full profiles and remaining matchups are linked below.
FAQ
Yes — Karthus holds the statistical advantage in this matchup. Karthus wins 57.6% of the recorded games.
57.6% from Karthus's perspective, measured on patch 16.13.1.
594 ranked games at Emerald rank and above, across all regions.
The current Karthus build — items, runes and skill order from the same data set — is on the Karthus build page.