

Kai’Sa vs Karthus Counter Pick
Matchup Summary
What the Data Means
This page breaks down the Kai’Sa vs Karthus matchup in League of Legends in the ADC role, using current ranked statistics. Across 564 recorded games on patch 16.13.1, Kai’Sa wins 42.6% of the time against Karthus. That places Karthus among Kai’Sa’s toughest opponents right now — the win rate sits clearly below the break-even line, which is exactly why this matchup is flagged as a counter.
Win rate and sample size are the two numbers to trust here: the more games behind a matchup, the more stable its rating from patch to patch. The stats refresh automatically every 48 hours from ranked games at Emerald and above, so this page always reflects the current meta rather than an old snapshot. For itemization and runes, open the current Kai’Sa build; both champions’ full profiles and remaining matchups are linked below.
FAQ
No — current data marks this as a counter matchup: Karthus has the statistical edge. Kai'Sa wins 42.6% of the recorded games.
42.6% from Kai'Sa's perspective, measured on patch 16.13.1.
564 ranked games at Emerald rank and above, across all regions.
The current Kai'Sa build — items, runes and skill order from the same data set — is on the Kai'Sa build page.